Two sample MR report
CD52_Alveolar Macrophages against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0489018 | 0.2183104 | 0.8371443 |
| Weighted median | 5 | 0.0607018 | 0.0161034 | 0.0001636 |
| Inverse variance weighted | 5 | 0.0623990 | 0.0126297 | 0.0000008 |
| Simple mode | 5 | 0.0585669 | 0.0222641 | 0.0581526 |
| Weighted mode | 5 | 0.0588038 | 0.0205032 | 0.0455588 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.5317048 | 3 | 0.9118728 |
| Inverse variance weighted | 0.5355400 | 4 | 0.9699502 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0064034 | 0.1033982 | 0.9545142 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.49e-05 | 0 | TRUE | 0.5809255 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
